GLOBAL DNA METHYLATION LEVELS IN WHITE BLOOD CELLS OF PATIENTS WITH CHRONIC HEROIN USE DISORDER. A PROSPECTIVE STUDY

Global DNA methylation levels in white blood cells of patients with chronic heroin use disorder. A prospective study

Background: Increasing scientific evidence shows the significant role of epigenetic mechanisms in drug use disorder, abstinence and relapse.Studies on human subjects are limited compared to those on animals, for various reasons such as poly-substance abuse, high drop-out rate and technical difficulties.Objectives: Our ALMOND SOAP goal was to evalua

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A Longitudinal Study of a Large Clinical Cohort of Patients with Lyme Disease and Tick-Borne Co-Infections Treated with Combination Antibiotics

The rising prevalence of tick-borne infections (TBIs) necessitates further attention.This study retrospectively investigated the types of TBIs, symptoms, Driver Safety Supplies and if combination antibiotics were helpful within a patient cohort at an infectious disease clinic in Ireland.In this chart audit of 301 individuals (184 female, 117 male)

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